Influence of Pregnancy on the Immune Response to Ragweed Antigen in Rats
Bibliographic record
Abstract
The reactivity of spleen lymphocytes in culture and the reaginic antibody (IgE) response to nondialyzable water-soluble ragweed (DWSR) extract were assessed at different intervals of pregnancy in rats. On day 6 of pregnancy, spleen cells showed a significant reduction in their mitogenic response to phytohemagglutinin (PHA) and slightly lowered response to concanavalin A (Con A) when compared to that of control nonpregnant rats. On day 11 of pregnancy, values obtained with PHA were slightly lower and those obtained with Con A similar to those of control rats. However, at day 18 of gestation, PHA values also returned to normal levels. In contrast, IgE antibody response to DWSR from day 4 to 9 of pregnancy was either slightly enhanced or similar to that of control rats and significantly suppressed from day 11 to 18 of gestation. The decline in humoral response to DWSR during late pregnancy is discussed in the text.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".