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Record W2076655894 · doi:10.1118/1.2241461

MO‐E‐ValB‐03: MRI‐Guided Focused Ultrasound

2006· article· en· W2076655894 on OpenAlexaff
Kullervo Hynynen

Bibliographic record

VenueMedical Physics · 2006
Typearticle
Languageen
FieldEngineering
TopicUltrasound and Hyperthermia Applications
Canadian institutionsSunnybrook Health Science Centre
Fundersnot available
KeywordsUltrasoundMagnetic resonance imagingFocused ultrasoundMedicineRadiologyBiomedical engineeringMedical physics

Abstract

fetched live from OpenAlex

Magnetic Resonance Imaging (MRI) provides such features as excellent soft tissue contrast, temperature sensitivity and ability to detect thermally coagulated tissue, that make it well suited for the guidance, control, and monitoring of thermal therapies. In this talk the current progress in MRI guided focused ultrasound thermal ablations and other non thermal interventions will be reviewed. The treatment of uterine fibroids has been approved by the FDA and is on its way to become routine. There are several other clinical trials in testing MRI guided focused ultrasound for the treatment of breast and other tumors. In addition, there is evidence that low thermal exposures controlled by MRI can be used to locally activate treatments. Finally, animal experiments show that ultrasound exposures can induce transient blood‐brain barrier disruption thus allowing targeted delivery of molecules such as chemotherapeutic agents in the brain.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.219
Teacher spread0.209 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2006
Admission routes1
Has abstractyes

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