MétaCan
Menu
Back to cohort
Record W2076833211 · doi:10.1002/ange.200803611

Sekundäre Alkylhalogenide in übergangsmetallkatalysierten Kreuzkupplungen

2009· article· de· W2076833211 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAngewandte Chemie · 2009
Typearticle
Languagede
FieldChemistry
TopicCatalytic Cross-Coupling Reactions
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsChemistryPolitical scienceGynecologyMedicine

Abstract

fetched live from OpenAlex

Abstract Sekundär, aber nicht zweitrangig : In den vergangenen fünf Jahren hat die Verwendung von sekundären Alkylhalogeniden in übergangsmetallkatalysierten Kreuzkupplungen erheblich zugenommen. Hier werden ausgewählte Beispiele für solche Prozesse unter Berücksichtigung von mechanistischen und stereochemischen Aspekten betrachtet. magnified image Es wurde viel Kraft in die Entwicklung von metallkatalysierten Kreuzkupplungen mit Alkylhalogeniden als elektrophile Reaktionspartner investiert. Während schon heute zahlreiche primäre Alkylhalogenide wirksam in Kreuzkupplungen verwendet werden können, stehen Umsetzungen mit sekundären Alkylhalogeniden gerade erst am Anfang. Hier werden ausgewählte Kreuzkupplungen vorgestellt, in denen sekundäre Alkylhalogenide als Elektrophile wirken. Dabei wird den verwendeten Übergangsmetallen, den Reaktionsmechanismen und dem stereochemischen Verlauf besondere Beachtung geschenkt.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.029
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.262
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it