SU‐E‐J‐83: Feasiblity of Real Time Tumour Tracking in Low Field MRI ‐ A Phantom Study
Bibliographic record
Abstract
Purpose: Real time adaptive radiotherapy of lung tumours is a promising application of the proposed hybrid Linac‐MR system. Several linac‐MR designs use low magnetic field strength (0.2T and 0.5T) imaging. Rapid real time imaging is potentially challenging due to the limited available contrast to noise ratio (CNR), especially at low MR fields. The goal of this phantom study is to quantitatively evaluate our in‐house tumour tracking algorithm with images of a moving lung tumour model with CNR equivalent to those obtained at 0.2T and 0.5T.Methods: A chest phantom with a moving lung compartment capable of 1D programmable motion is built. The lung compartment is loaded with mixtures containing MnCl2 and CuSO4 that simulates lung tumour/ healthy lung tissue by mimicking their relaxation properties at 0.2Tand 0.5T in the available 3T scanner. CNR of the acquired images is scaled down to 0.2T and 0.5T by addition of Gaussian noise. Dynamic bSSFP images (4 frames/s) are acquired with the lung compartment undergoing a series of pre‐programmed motion pattern based on patient data. An optical encoder is used to provide an independent reference measurement of phantom position while the lung compartment undergoes motion. In‐house automatic tumour tracking software is used to contour the tumour off‐line. The automatic contours are compared against user defined contours by evaluation of the centroid position error, and the Dice coefficient.Results: The average RMS errors of the contour centroids are < 0.5 mm and < 0.8 mm in all of our motion patterns in 0.5T CNR and 0.2T CNR images, respectively. Agreement with the user defined contours is excellent, with a dice coefficient of > 0.9 at both CNR levels Conclusions: Our auto‐contouring algorithm is able to accurately track a moving tumour with the limited CNR available from real time, low field MR sequences.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".