A Novel Translational Total Body Irradiation Technique
Bibliographic record
Abstract
A novel translating bed total body irradiation treatment delivery technique that employs dynamically shaped beams is presented. The patient is translated along the floor on a moving bed through a stationary radiation beam and the shape of the radiation beam is changed dynamically as the patient is moved through it, enabling compensation for local variations in patient thickness and tissue density. We demonstrate that the use of dynamically shaped beams results in greatly improved dose homogeneity compared with standard techniques, which use a single static beam shape. Along a representative dose profile through the lungs of a mock-human body, the maximum range of dose deviation from the average is 5.6% (from +2.7% to −2.9%) for the dynamic beam technique compared with 12.8% (from +3.6% to −9.2%) for the static beam technique. A novel, dual-interlock system that prevents bed motion when the radiation beam is stopped and stops the radiation beam when the bed motor is stopped has also been developed. The dual-interlock not only enhances the safety of the treatment but also ensures accuracy in the delivery of the treatment.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".