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Record W2078362131 · doi:10.1159/000180422

Orosomucoid and Haptoglobin Excretion in Rat Glomerulonephritis and Tubulonephritis

2008· article· en· W2078362131 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

Venue˜The œNephron journals/Nephron journals · 2008
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtein Interaction Studies and Fluorescence Analysis
Canadian institutionsUniversité Laval
FundersInstitut National de la Santé et de la Recherche Médicale
KeywordsOrosomucoidHaptoglobinUrineRadial immunodiffusionMedicineEndocrinologyGlomerulonephritisInternal medicineProteinuriaExcretionUrinary systemGlycoproteinImmunologyChemistryBiochemistryKidneyAntibody

Abstract

fetched live from OpenAlex

Haptoglobin and orosomucoid were detected and measured in concentrated normal rat urine by radial immunodiffusion. Normal haptoglobin clearance was 33 nl/min (190 nl/ min/kg) and normal orosomucoid clearance 146 nl/min (840 nl/ min/kg). During nephrotoxic serum glomerulonephritis both glycoproteins increased considerably in urine in two phases; in serum, after an early peak, haptoglobin returned to the normal level and orosomucoid fell below the normal value. During mercuric chloride tubulonephritis, an early sharp peak of both glycoproteins was observed chiefly in urine but also in serum.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.825
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.268
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it