Have Progression-Free Survival and Cancer-Specific Survival in Bladder Tumors Changed in Recent Decades?
Bibliographic record
Abstract
Background: To find out whether, despite greater surgical experience and lower perioperative mortality, PFS (progression free survival) and CSS (cancer-specific survival) due to bladder tumors have undergone variations in the last 30 years and the attributable causes. An objective is also to determine which risk factors can influence the evolution of muscle invasive bladder cancer (MIBC). Methods: A retrospective study of 599 patients who underwent radical cystectomy between 1975 and 2007. Firstly we performed a study of the conduct of all the studied variables throughout the nearly four decades studied. In order to determine which factors could predict progression and death due to bladder tumors a univariate and multivariate study was performed on the 563 patients who underwent radical cystectomy. Results: No differences were observed in PFS nor CSS over the four periods studied. On the contrary if there has been a decrease in surgical complications. Only two variables retained independent prognostic value in multivariate analysis both in PFS and CSS; pathological organ confinement and lymph node involvement . Conclusions: No significant differences were observed in progression free survival and in cancer- specific survival in patients who underwent cystectomy for bladder cancer over the four periods studied. Non organ confinement and lymph node involvement in the radical cystectomy specimen are the factors that maintain independent prognostic value for cancer-specific survival and progression-free survival in the multi-variate analysis. doi: http://dx.doi.org/10.4021/wjnu92w
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".