Diminutive but Dangerous: A Case of a Polypoid Rectal Arteriovenous Malformation
Bibliographic record
Abstract
Arteriovenous malformations (AVMs) of the gastrointestinal tract - entities that are distinct from angiodysplasia and venous varices - present with acute blood loss or chronic anemia. They have been reported in both the upper and lower gastrointestinal tract after hemorrhage, or are found incidentally. However, polypoid AVMs are unusual, with only seven cases having been reported to date [ 1 ] [ 2 ] [ 3 ] [ 4 ] [ 5 ], three of which were colonic. A 24-year-old healthy Oriental male presented with hematochezia. Flexible sigmoidoscopy revealed blood and feces throughout the left colon. A 99 Tc red blood cell scan disclosed active bleeding in the rectosigmoid region. Repeat endoscopy revealed active bleeding in the rectum, coming from a 7-mm polypoid lesion (Figure [ 1 ]). Hemostasis was achieved after injecting 3 ml of 1 : 10 000 epinephrine at the base and tipp of the lesion. At a repeat sigmoidoscopy three days later, the lesion was snared and cauterized. The histological findings were diagnostic for an AVM (Figure [ 2 ]). There has been no further bleeding. Figure 1 Colonoscopic view of the bleeding rectal lesion after basal injection of 1 ml of 1 : 10 000 epinephrine Figure 2 Photomicrograph of the polypectomy specimen, showing a collection of thick and thin-walled blood vessels in the submucosa, with extension into the lamina propria (elastic stain, original magnification × 50) Previously reported noncolonic polypoid AVMs have included lesions in the mid-ileum [ 1 ] and stomach [ 2 ] [ 3 ]. Koziara et al. [ 4 ] reported the first polypoid colonic AVMs in the sigmoid and transverse colons. More recently, Park et al. [ 5 ] described a 1-cm pedunculated polyp in the descending colon causing massive bleeding. The patient with hematochezia whose case is reported here is both the youngest with a polypoid colonic AVM so far reported, and the only reported rectal case. The patient was Korean, as was the patient reported by Park et al. [ 5 ]. No conclusions concerning any ethnic predisposition can be made for this rare entity on the basis of only two reports, but it is curious that both shared the same ethnicity. The size of lesions that can be safely transected using endoscopic snare polypectomy is not known. It has been suggested that vessels > 1 mm in diameter should be treated with caution [ 4 ], although Koziara et al. [ 4 ] reported safely transecting vessels of 3 mm. In our experience, it is important to exercise caution when carrying out polypectomy on a suspected vascular lesion.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.007 |
| Meta-epidemiology (narrow) | 0.003 | 0.002 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.004 | 0.004 |
| Science and technology studies | 0.003 | 0.003 |
| Scholarly communication | 0.002 | 0.003 |
| Open science | 0.002 | 0.003 |
| Research integrity | 0.009 | 0.005 |
| Insufficient payload (model declined to judge) | 0.003 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".