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Cognitive and Behavioural Disorders of Epileptic Origin in Children

2006· article· en· W2080990214 on OpenAlexaffabout
Keith J. Goulden

Bibliographic record

VenueJournal of Developmental & Behavioral Pediatrics · 2006
Typearticle
Languageen
FieldMedicine
TopicEpilepsy research and treatment
Canadian institutionsGlenrose Rehabilitation HospitalUniversity of Alberta
Fundersnot available
KeywordsEpilepsyCognitionPsychologyArgument (complex analysis)Intervention (counseling)Set (abstract data type)Theme (computing)PsychiatryAffect (linguistics)MedicinePsychotherapistComputer science

Abstract

fetched live from OpenAlex

Cognitive and Behavioural Disorders of Epileptic Origin in Children, by Thierry Deonna and Eliane Roulet-Perez, West Nyack, NY, Cambridge University Press, 2005, 241 pp., $90.00 hardcover. This is number 168 of the Clinics in Developmental Medicine series from Mac Keith Press, and is a worthwhile addition to a very useful set of reference books and reviews. Its focus on the developmental and behavioral aspects of epilepsy should be of interest to many of us involved in Developmental-Behavioral Pediatrics, whether we are directly involved in an epilepsy service or not. The authors have long and extensive personal experience both in the clinical care of children with epilepsy and in research on the topic. They make a strong case for the possibility that some cognitive-behavioral disorders in some children are the result of epilepsy, and may therefore be treatable with anticonvulsants (or surgery) of one kind or another. The book includes both an extensive review of the literature and numerous clinical anecdotes or case examples that illustrate and enhance the authors' arguments. They emphasize that this approach does not replace more traditional scientific approaches using groups randomized to intervention, but may give clues that can direct future research of this more rigorous type (the foreword by Jean Aicardi, one of the giants in the field of childhood epilepsy, presents a convincing argument in support of this approach). The over-riding theme of the book is that epilepsy can directly affect brain function (both chronically and intermittently) and may therefore have a direct effect on behavior in addition to that mediated through psychosocial and family stresses. Their case is made convincingly, given the authors' evident experience in the area and strong research background. The length of follow-up and richness of assessment data on individual cases in impressive. I was asked to comment on the book's sensitivity to issues of culture, and there are no specific cultural references in the book. There are, however, numerous comments in the case examples that indicate the authors' support for families in the difficult choices they must make regarding investigation and treatment (cases are included in which the "research protocol" was breached: incomplete evaluations, refusal or discontinuation of therapy, etc). This book can be read from beginning to end, as it is organized in a logical order with successive chapters building on the previous. It is well written and engaging. There are, however useful descriptive chapter headings for the reader looking for reference to a particular issue (epilepsy surgery, specific epilepsy syndromes, educational aspects, etc). There is a brief appendix listing neuropsychologic tests, and a reasonably up-to-date reference list. One of the reasons given for this book's "anecdotal" approach is that children with these conditions are uncommon and each clinical situation is unique. The general issues raised by the cases, however, arise fairly frequently in the assessment and management of children with complex developmental-behavioral disorders: the management of recognized epilepsy paying attention to cognitive side-effects; the assessment of children with intermittent dysfunction; the investigation and treatment of children with a history of regression. Although the authors do not give definitive answers to these difficult clinical problems, they present a logical and reasonable approach that is grounded both in research literature and extensive clinical experience. Keith J. Goulden, M.D. Division of Neurodevelopmental/Neuromotor Pediatrics Glenrose Rehabilitation Hospital and University of Alberta Edmonton, Alberta

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.535

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.315
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2006
Admission routes2
Has abstractyes

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