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Record W2081093096 · doi:10.1089/cbr.2000.15.7

Radiobiology of Low-Dose-Rate Radiation Relevant to Radioimmunotherapy

2000· review· en· W2081093096 on OpenAlexaff
Albert Murtha

Bibliographic record

VenueCancer Biotherapy and Radiopharmaceuticals · 2000
Typereview
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsAlberta Cancer Foundation
Fundersnot available
KeywordsRadioimmunotherapyRadiobiologyRadiation therapyMedicineDose rateNuclear medicineMedical physicsExternal beam radiationOncologyRadiologyImmunology

Abstract

fetched live from OpenAlex

Systemically delivered targeted radioisotopes are being used ever-increasingly for cancer therapy. Compared with conventional external beam radiation therapy, the radiation dose-rate associated with these novel systemic therapies is approximately two orders of magnitude lower in intensity (dose-rate). Hence it is referred to as low dose-rate (LDR) radiotherapy. An awareness of the unique radiobiology associated with LDR-based therapy provides a basis for cautious enthusiasm as these new therapies are explored.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.993
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.412
Teacher spread0.378 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2000
Admission routes1
Has abstractyes

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