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Record W2081225239 · doi:10.1159/000175921

2,5 und 5 mg Cilazapril einmal täglich verglichen mit Plazebo bei Hypertonie

2008· article· de· W2081225239 on OpenAlex
Y. Lacourci egrave re, Luc Poirier, Myron Pyzyk

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCardiology · 2008
Typearticle
Languagede
FieldMedicine
TopicBlood Pressure and Hypertension Studies
Canadian institutionsCentre hospitalier de l'Université LavalRoche (Canada)
Fundersnot available
KeywordsCilazaprilGynecologyMedicineBlood pressureInternal medicineACE inhibitorAngiotensin-converting enzyme

Abstract

fetched live from OpenAlex

Bei Patienten mit leichter bis mittelschwerer essentieller Hypertonie wurde die 24stündige antihypertensive Wirksamkeit von 2,5 und 5 mg Cilazapril durch ambulantes Blutdruck-Monitoring mit Plazebo verglichen. Durch beide Regime wurde nach 4wöchiger Behandlung eine etwa gleiche Senkung des mittleren ambulanten 24-Stunden- und des Tageszeitblutdrucks erreicht. Darüber hinaus betrug der Prozentsatz der Patienten, deren Blutdruck kontrolliert wurde (durchschnittlicher ambulanter Tages-zeitblutdruck < 90mm Hg), in der Plazebogruppe 14%, unter 2,5 und 5 mg Cilazapril 64 bzw. 71 %. Weiterhing lag auch der Prozentsatz der Blutdruck-Loads in beiden Regimen ähnlich (29 bzw. 36%). Diese Ergebnisse besagen, dass 2,5 und 5 mg Cilazapril hinsichtlich der ambulanten Blutdrucksenkung gleich wirksam sind.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.817
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.275
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it