Validation of an ontological medical decision support system for patient treatment using a repository of patient data
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
In this article, we begin by presenting OMeD, a medical decision support system, and argue for its value over purely probabilistic approaches that reason about patients for time-critical decision scenarios. We then progress to present Holmes, a Hybrid Ontological and Learning MEdical System which supports decision making about patient treatment. This system is introduced in order to cope with the case of missing data. We demonstrate its effectiveness by operating on an extensive set of real-world patient health data from the CDC, applied to the decision-making scenario of administering sleeping pills. In particular, we clarify how the combination of semantic, ontological representations, and probabilistic reasoning together enable the proposal of effective patient treatments. Our focus is thus on presenting an approach for interpreting medical data in the context of real-time decision making. This constitutes a comprehensive framework for the design of medical recommendation systems for potential use by medical professionals and patients both, with the end result being personalized patient treatment. We conclude with a discussion of the value of our particular approach for such diverse considerations as coping with misinformation provided by patients, performing effectively in time-critical environments where real-time decisions are necessary, and potential applications facilitating patient information gathering.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it