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Record W2082319081 · doi:10.1118/1.3476164

Poster — Thur Eve — 59: Improving Treatment Delivery Efficiency in Lung SBRT with a VMAT Approach

2010· article· en· W2082319081 on OpenAlexaff
D Comsa, Thomas G. Purdie, D Moseley

Bibliographic record

VenueMedical Physics · 2010
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsPrincess Margaret Cancer Centre
Fundersnot available
KeywordsMedicineNuclear medicineArc (geometry)Lung cancerRadiation treatment planningLungDosimetryStage (stratigraphy)Radiation therapyRadiologyOncologyInternal medicineMathematics

Abstract

fetched live from OpenAlex

Lung SBRT has demonstrated excellent local control and low toxicity for patients with medically inoperable, early stage non‐small‐cell lung cancer (NSCLC). The promising clinical lung SBRT results have been achieved using a variety of hypofractionated dose regimens and localization/immobilization techniques; however treatment delivery times have been consistently long. Volumetric modulated arc therapy (VMAT) is a variable dose rate delivery method which has the potential for increased treatment delivery efficiency, as it allows continuous irradiation of the target with the gantry rotating around the patient. A retrospective planning study (n = 10) demonstrates VMAT as a promising technique to produce dose distributions similar or, in most cases, superior to those achieved with the 3D conformai SBRT plans currently used in our clinic for early stage NSCLC treatments. Single arc and non‐coplanar 2 arc VMAT approaches lead to improved conformity of both the high and low dose around the target and lower V20 and V5 values for the healthy lung. In spite of the significantly increased number of monitor units for the VMAT plans, this study shows treatment delivery time improvements (n = 2) of 45% for the single arc configurations compared with 3D conformai static delivery. A second non‐coplanar partial arc can be used to further increase conformity of the high dose surrounding the target and better avoid organs at risk, with a delivery efficiency improvement of 25% for the 2‐arc configurations compared with static delivery. Finally, treatment delivery accuracy with VMAT was similar to that of conformal static plans.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.015
Threshold uncertainty score0.051

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0150.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.247
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

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