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Record W2082588141 · doi:10.1186/1546-0096-10-s1-a92

Orbital myositis: a report of 3 pediatric cases

2012· article· en· W2082588141 on OpenAlexaff
Gaëlle Chédeville, Rosie Scuccimarri

Bibliographic record

VenuePediatric Rheumatology · 2012
Typearticle
Languageen
FieldMedicine
TopicIgG4-Related and Inflammatory Diseases
Canadian institutionsMontreal Children's Hospital
Fundersnot available
KeywordsMedicineMyositisInferior rectus muscleRheumatologyDiplopiaMicrocytic anemiaInternal medicineMedial rectus muscleGastroenterologyAnemiaSurgery

Abstract

fetched live from OpenAlex

An 8 yo boy was referred to our clinic in March 2008 for 2 episodes of orbital myositis. The first episode occurred in November 2007 and involved the left eye. Investigations with a CT scan and an MRI revealed changes in the left lateral rectus muscle, felt to be consistent with a myositis. This spontaneously resolved over a few days. In January 2008, the child’s right eyelid became swollen and he had an associated diplopia. The MRI revealed a normal left rectus muscle but inflammation was observed in the right rectus muscle. Again, without treatment, the symptoms resolved. It was at that time that the patient was referred to Rheumatology. On review of systems, he was noted to have longstanding epigastric pain associated with meals. His physical examination was unremarkable. Blood tests revealed iron deficiency, microcytic anemia and an elevated ESR. He was referred to Gastroenterology. He underwent an endoscopy which confirmed the diagnosis of Crohn’s disease. There has been no recurrence of the orbital myositis since the Crohn’s disease has been in remission. A 15 yo girl presented with acute onset of right eye swelling in May 2010. Six months prior, she had a similar episode that lasted for one week and resolved on its own. Imaging studies revealed changes in the right medial rectus muscle consistent with myositis. A review of systems was completely unremarkable. The physical examination revealed only a right upper eyelid swelling. A full work-up was done which was completely normal. She was started on oral steroids and had a very good response within days. She remains well off prednisone and has not developed any systemic symptoms. A 14 yo boy presented with left eye swelling in June 2010. The diagnosis of orbital myositis was confirmed on CT scan, which showed involvement of all the extra-ocular muscles, mainly the medial rectus. The review of systems was significant for recurrent mouth ulcers and poor growth. A work-up was performed which was normal except for a mild anemia and an elevated ESR. Symptoms resolved on prednisone. Six months later, he presented with a new episode of left orbital myositis. On examination, he had marked oral ulcers with significant lip swelling. He underwent an endoscopy which did not demonstrate any signs of colonic inflammation. Due to a high suspicion for Crohn’s disease, the patient is now awaiting a capsule endoscopy. Once again, he has had an excellent response to prednisone. Orbital myositis is a rare condition in children. These cases are usually referred to Rheumatology to investigate for a possible underlying condition and for initiation of immunosuppressive therapy. Although most cases are idiopathic, a complete work-up is warranted in these patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.091
Threshold uncertainty score0.809

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.268
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2012
Admission routes1
Has abstractyes

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