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Record W2083580496 · doi:10.3899/jrheum.090125

Clinical Implications of Understanding Radiographic Findings in Relation to Clinical Outcomes in Rheumatoid Arthritis

2009· review· en· W2083580496 on OpenAlexfundvenueno aff
Ed Keystone

Bibliographic record

VenueJournal of Rheumatology Supplement · 2009
Typereview
Languageen
FieldMedicine
TopicRheumatoid Arthritis Research and Therapies
Canadian institutionsnot available
FundersBristol-Myers Squibb CanadaBristol-Myers Squibb
KeywordsMedicineRheumatoid arthritisRadiographyAntirheumatic drugsClinical diseaseInternal medicineDiseaseClinical trialPhysical therapyAntirheumatic AgentsSurgery

Abstract

fetched live from OpenAlex

The clinical progression of rheumatoid arthritis (RA) and longterm response to therapy is generally assessed by quantifying changes in joint space narrowing and erosions visible on serial plain radiographs. In patients treated with classic disease modifying antirheumatic drugs, the joint damage seen on radiographic images is usually directly associated with longterm functional disability. However, this relationship is not as clearly defined in patients treated with biologic agents. The apparent dissociation between clinical and radiologic outcomes in patients with RA who are treated with biologic therapies needs to be taken into consideration when evaluating the efficacy of treatment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.630
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0060.002
Bibliometrics0.0030.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.110
GPT teacher head0.437
Teacher spread0.328 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2009
Admission routes2
Has abstractyes

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