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Record W2084300407 · doi:10.1016/j.jff.2012.10.004

Fried egg digest decreases blood pressure in spontaneous hypertensive rats

2012· article· en· W2084300407 on OpenAlexafffund
Kaustav Majumder, Sareh Panahi, Susan Kaufman

Bibliographic record

VenueJournal of Functional Foods · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtein Hydrolysis and Bioactive Peptides
Canadian institutionsUniversity of Alberta
FundersEgg Farmers of Canada
KeywordsBlood pressureCircadian rhythmIn vivoEndocrinologyInternal medicineRenin–angiotensin systemBody weightMedicineChemistryBiology

Abstract

fetched live from OpenAlex

Our previous study showed that in vitro simulated gastrointestinal digestion of fried whole egg (FWE) released several peptides with angiotensin converting enzyme-I (ACE-I) inhibitory properties. The present study evaluated in vivo blood pressure lowering effect of FWE digest in spontaneously hypertensive rats (SHR). Twelve to fourteen weeks old male SHRs were surgically implanted with telemetric blood pressure (BP) measuring devices. After one week recovery, animals were randomly allocated to three groups at dosage of FWE digest 0 (control), 100, and 1000 mg of FWE digest/kg body weight for 3 days ( n = 8), and the BP was recorded continuously. The 1000 mg/kg BW group showed a significant decrease in BP and also rectified the impaired circadian blood pressure rhythm compared to the control group. This study indicates a potential blood pressure lowering effect of egg consumption.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.229
Threshold uncertainty score0.420

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.232
Teacher spread0.218 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2012
Admission routes2
Has abstractyes

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