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Record W2085177991 · doi:10.1586/17474108.2.5.587

Novel drug-delivery strategies for the treatment of ovarian cancer

2007· article· en· W2085177991 on OpenAlexaff
Emmanuel A. Ho, Christine Allen, Micheline Piquette‐Miller

Bibliographic record

VenueExpert Review of Obstetrics & Gynecology · 2007
Typearticle
Languageen
FieldMedicine
TopicOvarian cancer diagnosis and treatment
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMedicineOvarian cancerOncologyDiseaseDrugChemotherapyDrug resistanceInternal medicineCancerIntensive care medicinePharmacology

Abstract

fetched live from OpenAlex

Ovarian cancer is one of the most lethal gynecologic malignancies in women. By the time the disease is detected, it will often have metastasized, making treatment more difficult. In patients undergoing chemotherapy, tumors initially appear responsive but most patients relapse with drug resistance. Therefore, present treatment therapies for women diagnosed with advanced ovarian cancer are poor and new approaches for treatment must be developed. Our objectives are to outline the obstacles encountered in treating ovarian cancer, the current treatment strategies and novel approaches that may improve therapeutic outcome.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.961
Threshold uncertainty score0.500

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.359
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes1
Has abstractyes

Explore more

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