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Record W2085218159 · doi:10.1086/503215

Creutzfeldt-Jakob Disease Management of Accidental Contamination of Neurosurgical Instruments, Pathology Equipment, and Solutions

2000· letter· en· W2085218159 on OpenAlexaff
Elizabeth Bryce, Katerina Dorovoni-Zis, Dianne Trudeau, Margaret Sinclair, F. J. Roberts

Bibliographic record

VenueInfection Control and Hospital Epidemiology · 2000
Typeletter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPrion Diseases and Protein Misfolding
Canadian institutionsVancouver Hospital and Health Sciences Centre
Fundersnot available
KeywordsAccidentalMedicineContaminationDiseaseAction (physics)PathologyMedical emergencyIntensive care medicineBiology

Abstract

fetched live from OpenAlex

To the Editor:We describe the measures taken to identify, triage, and decontaminate equipment and solutions following a brain biopsy on a previously unidentified case of Creutzfeldt-Jakob disease (CJD).Immediately after the neuropathologist notified the Infection Control Department of the positive histopathology for CJD, the Sterile Supply Department and Neurosurgical Operating Room staff reviewed the operating room records and determined that a ventriculogram set and a craniotomy set (including the Midas-Rex drill and bits and Roton dissectors) had been used.The washed equipment was located, along with other neurosurgical items, on a cart washer, awaiting sterilization.All potentially contaminated neurosurgical equipment processed with the CJD case was labeled "CJD Precautions," autoclaved at 134°C for 18 minutes, and isolated pending a decision regarding its fate.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.037
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.017
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0020.002
Open science0.0020.001
Research integrity0.0370.019
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.266
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2000
Admission routes1
Has abstractyes

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