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Record W2085448923 · doi:10.1038/modpathol.2013.81

Next-generation biobanking of metastases to enable multidimensional molecular profiling in personalized medicine

2013· article· en· W2085448923 on OpenAlexafffund
Zuanel Diaz, Adriana Aguilar‐Mahecha, Éric R. Paquet, Mark Basik, Michèle Orain, Errol Camlioglu, André Constantin, Naciba Benlimame, Dimcho Bachvarov, Guillaume Jannot, Martin J. Simard, Benoı̂t Chabot, Adrian Gologan, Roscoe Klinck, Thérèse Gagnon-Kugler, Bernard Lespérance, Benoît Samson, Petr Kavan, Thierry Alcindor, Richard Dalfen, Cathy Lan, Catherine Chabot, Marguerite Buchanan, Ewa Przybytkowski, Samia Qureshi, Caroline Rousseau, Alan Spatz, Bernard Têtu, Gerald Batist

Bibliographic record

VenueModern Pathology · 2013
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCancer Genomics and Diagnostics
Canadian institutionsSt Mary's Hospital CentreHôpital du Sacré-Cœur de MontréalUniversité de SherbrookeUniversité LavalMcGill University Health CentreHôpital du Saint-SacrementHôpital Charles-Le MoyneHôtel-Dieu de QuébecMcGill UniversityJewish General HospitalQuebec - Clinical Research Organization in Cancer
FundersCanadian Institutes of Health ResearchSanofiPfizer
KeywordsBiobankContext (archaeology)Liquid biopsyMedicinePersonalized medicineComputational biologyPathologyBioinformaticsComputer scienceCancerBiologyInternal medicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0000.000
Scholarly communication0.0020.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.270
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations42
Published2013
Admission routes2
Has abstractno

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