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Record W2085577773 · doi:10.2460/javma.243.5.649

Thiamine deficiency in dogs and cats

2013· article· en· W2085577773 on OpenAlexaboutno aff
Jessica E. Markovich, Cailin R. Heinze, Lisa M. Freeman

Bibliographic record

VenueJournal of the American Veterinary Medical Association · 2013
Typearticle
Languageen
FieldMedicine
TopicAlcoholism and Thiamine Deficiency
Canadian institutionsnot available
Fundersnot available
KeywordsCATSThiamineThiamine deficiencyMedicinePhysiologyInternal medicine

Abstract

fetched live from OpenAlex

Vet Med Today: Timely Topics in Nutrition 649 I past years, nutritional deficiencies were considered to be an important problem in dogs and cats. Currently, most pet owners in many countries, such as the United States and Canada, feed nutritionally balanced commercial pet foods. As a result, nutritional deficiencies have become uncommon because reputable pet food manufacturers regularly test their products to ensure that they contain adequate amounts of all nutrients. Anecdotally, most reported deficiencies currently arise from animals eating incomplete or unbalanced homemade, vegetarian, or raw meat diets. Therefore, veterinarians may not consider deficiencies as differential diagnoses in animals eating traditional commercial diets. However, thiamine (vitamin B 1 ) deficiency is of clinical concern even today. Since 2009, there have been 5 major voluntary pet food recalls involving thiaminedeficient pet foods in the United States that ultimately involved 9 brands of cat foods and at least 23 clinically affected cats. Most of these recalls were instituted in response to a report from a consumer or veterinarian after treating a cat that had clinical signs consistent with thiamine deficiency. In addition to the possibility of a deficiency in commercial pet foods, there are a variety of situations in which a deficiency may arise in dogs or cats with medical conditions. Clinical manifestations of a deficiency of thiamine are variable, and the disease is likely underreported because of the wide array of clinical signs in combination with a lack of specific clinicopathologic changes detected via laboratory analysis. Thiamine has received much attention as a vitamin deficiency that is common in ruminants, primarily as a result of rumen bacterial inactivation of the vitamin, which results in characteristic cerebrocortical necrosis and neurologic signs. Dogs and cats can also be affected by deficiency of this vitamin because of an inability to endogenously synthesize large quantities of thiamine. Therefore, both cats and dogs need to have a consistent dietary supply of thiamine. As with all B vitamins, thiamine is water soluble, stored in the body in small amounts, and subject to urinary losses. Thiamine is also particularly labile and easily destroyed by typical foodprocessing techniques. In fact, many early experiments Thiamine deficiency in dogs and cats

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.292
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations42
Published2013
Admission routes1
Has abstractyes

Explore more

Same venueJournal of the American Veterinary Medical AssociationSame topicAlcoholism and Thiamine DeficiencyFrench-language works237,207