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Record W2086020608 · doi:10.1159/000121140

Choices in the 1990s for the Management of Pediatric Cerebral Arteriovenous Malformations

2008· article· en· W2086020608 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenuePediatric Neurosurgery · 2008
Typearticle
Languageen
FieldMedicine
TopicVascular Malformations Diagnosis and Treatment
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsMedicineArteriovenous malformationRadiosurgeryEmbolizationLesionStroke (engine)PediatricsEpilepsySurgeryRadiation therapy

Abstract

fetched live from OpenAlex

A retrospective 45-year analysis of the management of 160 children with intracranial arteriovenous malformations at The Hospital for Sick Children, Toronto, reveals substantially improving outcomes which relate to more efficient diagnoses and treatments. 80% of children will declare their malformation by means of spontaneous intracranial hemorrhage. For those children who present with hemorrhage or epilepsy, 80% will require an operation. The overall mortality rate has declined to 12% since 1975 and that for the cerebellar lesions from 67 to 42%. 53% of the patients operated upon will be neurologically normal. Endovascular embolization of a child's AVM is a customized, partial solution for a limited number of children. Stereotactic radiosurgery will be used increasingly to obliterate those small lesions in children which are unassociated with hemorrhage or are the residua of an operation. As many as 10% of children (15/160) with diagnosed AVMs cannot be helped with operative or other interventional therapies. The recognition of the pediatric stroke syndromes, the early triage and diagnosis of a child's cerebral hemorrhage, the operative and anaesthetic technologies and the adjunct therapies - choices of the nineties - have resulted in a 66% decline in the overall mortality from this vascular lesion as well as greater assuredness that for most the lesion can be permanently obliterated.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.323

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.261
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it