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Record W2086838260 · doi:10.1016/j.carj.2013.09.004

The Emergence of Ultra-Low–Dose Computed Tomography and the Impending Obsolescence of the Plain Radiograph?

2013· review· en· W2086838260 on OpenAlexaff
Patrick D. McLaughlin, Hugue A. Ouellette, Luck J. Louis, Paul I. Mallinson, Timothy O’Connell, John R. Mayo, Peter L. Munk, Savvas Nicolaou

Bibliographic record

VenueCanadian Association of Radiologists Journal · 2013
Typereview
Languageen
FieldMedicine
TopicRadiation Dose and Imaging
Canadian institutionsVancouver General Hospital
Fundersnot available
KeywordsMedicineObsolescenceComputed tomographyRadiologyNuclear medicineMedical physics

Abstract

fetched live from OpenAlex

Until recently, computed tomographic (CT) examinationsacquired at a radiation exposure equivalent to correspondingplain radiographs would be of grossly substandard imagequality, almost certainly resulting in a failure to adequatelyvisualize many anatomic structures. Over the past decade,successive technical breakthroughs have facilitateddiagnostic-quality CTs to be acquired at rapidly decliningionizing radiation exposures. Today, the mean effectivedose of a radiographic series of the abdomen at 0.7 mSv,pelvis at 0.6 mSv, thoracic and lumbar spine at 1.0 and1.5 mSv, respectively [1] appear licentious when comparedwith exposures achieved in recent low-dose CT trials(Table 1). In an era in which low-dose CT has facilitateda 20% reduction in mortality among smokers [7]. and inwhich doses continue to substantially fall, we propose thatradiologists and clinicians should critically reevaluate therisks and benefits of performing many plain radiographicexaminations.Technical BackgroundIn brief summary, there have been 3 key developments inCT dose reduction technology that have facilitated theaforementioned trend. Automated exposure control ensuresefficient dose delivery by modulating tube current accordingto patient width and attenuation profile [8e10]. Fixed tubecurrent settings were commonplace in older-generation CTsystems and resulted in wider, more attenuating areas, suchas the shoulders receiving the same exposure as narrower lessattenuating regions such as the upper lungs. More recently,algorithms that modulate CT voltage according to patientsize and CT application have also been implemented withgood success [11].After ensuring efficient dose delivery, the largest chal-lenge to obtaining diagnostically acceptable CT images atexposure levels similar to plain radiographs is the severity ofrandom variation in attenuation values that occur within thenormal anatomic structures in these images otherwiseknown as noise. The magnitude of image noise at low CTexposure is fundamentally related to the image reconstruc-tion process [12]. Iterative reconstruction algorithms usea varyingly complex model of the physical characteristics ofthe x-ray tube, beam, and the 3-dimensional interaction ofthe x-ray beam within the patient to reduce noise and areclearly better than more traditional methods of reconstruc-

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.825
Threshold uncertainty score0.496

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.277
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations26
Published2013
Admission routes1
Has abstractyes

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