Effects of Soy Protein and Isoflavones Intake on HDL Metabolism in Asian Populations
Bibliographic record
Abstract
High-density lipoprotein (HDL) has been shown to have a variety of functions that contribute to anti-atherogenesis. Therefore, low HDL-cholesterol (HDL-C) level is significantly associated with the development of coronary artery diseases (CADs). Soy and isoflavones have been proposed to reduce the risk of CAD. However, the underlying mechanisms for soy and isoflavone-induced reduction of coronary risks remain largely unknown. To understand effects of lifestyle on lipids metabolism, the existence of interracial differences should be considered. Here we reviewed published articles about effects of soy and isoflavone intake on HDL metabolism. We regarded systematic review and meta-analysis and also clinical studies which were performed in Asian populations as important articles in this review. Evidences obtained from clinical trials performed in Asian populations showed that effects of soy protein and isoflavones on HDL-C were limited, which may be due to limited studied population such as postmenopausal women. Meta-analyses indicated that intake of soy protein and isoflavones is beneficially associated with HDL metabolism. J Endocrinol Metab. 2014;4(3):51-55 doi: http://dx.doi.org/10.14740/jem224w
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".