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Record W2087140773 · doi:10.1109/sensor.2007.4300255

An Investigation on a Vibration-Based Active Protein Desorption Mechanism for Implantable MEMS-Based Biosensor Applications

2007· article· en· W2087140773 on OpenAlexaff
Po-Ying Yeh, Mu Chiao, Jayachandran N. Kizhakkedathu

Bibliographic record

VenueTRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference · 2007
Typearticle
Languageen
FieldEngineering
TopicMicrofluidic and Bio-sensing Technologies
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMicroelectromechanical systemsDesorptionMaterials scienceAdsorptionBiosensorPolymerBiocompatible materialBovine serum albuminMembraneProtein adsorptionOptoelectronicsNanotechnologyChromatographyChemistryBiomedical engineeringComposite materialEngineering

Abstract

fetched live from OpenAlex

This paper presents for the first time an active protein desorption mechanism initiated by a MEMS vibrating membrane. Unlike conventional, passive biocompatible polymer coatings, active micromachined lead zircornate titanate (PZT) plate is used to generate an acoustic streaming force for minimizing the protein adsorption on a SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> surface. Preliminary in vitro testing showed that 57plusmn10% of adsorbed bovine serum albumin (BSA) and 47plusmn13% of IgG were effectively removed from a vibrating surface. A simulation study on the vibration-frequency spectrum indicates the resonant frequency at 274 kHz matches well with the experimental data.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.467
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.251
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes1
Has abstractyes

Explore more

Same venueTRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems ConferenceSame topicMicrofluidic and Bio-sensing TechnologiesFrench-language works237,207