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Record W2087219219 · doi:10.1186/cc14076

Endotoxin Activity Assay levels correlate with the microbiological results of Gram-negative organisms in septic patients

2014· article· en· W2087219219 on OpenAlexaboutno aff
Mihoko Tsunoda, Mi‐Ri Kang, M. Saito, Noriko Saito, M Namiki, Tomoyuki Harada, Munekazu Takeda, Arino Yaguchi

Bibliographic record

VenueCritical Care · 2014
Typearticle
Languageen
FieldMedicine
TopicSepsis Diagnosis and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineGramSepsisGram-negative bacteriaMicrobiologyAntibodySeptic shockImmunologySevere sepsisInternal medicineBacteriaEscherichia coliBiologyBiochemistry

Abstract

fetched live from OpenAlex

The Endotoxin Activity Assay (EAA™; Spectral Diagnostics Inc., Toronto, Canada) is a useful diagnostic test for sepsis due to Gram-negative infection and is based on the reaction of neutrophils to endotoxin complexed with an anti-endotoxin antibody. However, the relations between values of EAA and microbiological data have not been elucidated. Our hypothesis is that EAA values correlate to the results of microbiological cultures and also severity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.041
Threshold uncertainty score0.295

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.326
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2014
Admission routes1
Has abstractyes

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