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Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease

2013· article· en· 147 citations· W2088424318 on OpenAlex· 10.1038/nature12415

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Post-publication record

Nature
Retraction
Reason
Error in Image;Falsification/Fabrication of Image;Manipulation of Images;Unreliable Image;
Date
7/17/2015 0:00
Flagged by OpenAlex?
Yes

Source: Retraction Watch, joined by DOI. OpenAlex records retraction as is_retracted, a boolean over a state space with at least four values, so it cannot express an expression of concern, a correction or a reinstatement — it reports them as false, which reads as “fine”.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature
Topic
Alzheimer's disease research and treatments
Field
Medicine
Canadian institutions
Funders
National Institute of Neurological Disorders and StrokeNational Institute of Mental HealthNational Institute on AgingTranslational Genomics Research InstituteNational Institutes of HealthCanadian Institutes of Health ResearchNorthern California Institute for Research and Education
Keywords
Apolipoprotein ETranscriptomeBiologyAlleleAlzheimer's diseaseGeneticsDiseaseNeuroscienceGeneGene expressionMedicineInternal medicine
Has abstract in OpenAlex
no