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Record W2088564719 · doi:10.1097/brs.0b013e3181b40d4f

False-Negative Transcranial Motor-Evoked Potentials During Scoliosis Surgery Causing Paralysis

2009· review· en· W2088564719 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueSpine · 2009
Typereview
Languageen
FieldMedicine
TopicIntraoperative Neuromonitoring and Anesthetic Effects
Canadian institutionsDiscovery Air (Canada)
Fundersnot available
KeywordsMedicineScoliosisParaplegiaParalysisSomatosensory evoked potentialSurgeryIntraoperative neurophysiological monitoringPerioperativeSpinal cord injuryAnesthesiaSpinal cord

Abstract

fetched live from OpenAlex

In Brief Study Design. Case report. Objective. To report a case of false-negative intraoperative motor-evoked potentials (MEP) that developed paraplegia after surgery. Summary of Background Data. Although several false-negative results have been reported with somatosensory-evoked potentials, there is no report noted with MEP. Therefore, several authors have preferred using MEPs as a gold standard in neuromonitoring. Methods. We report a case of false-negative MEP during the scoliosis surgery which is the first report showing false-negative MEPs during operation. Results. A 15-year-old girl with severe kyphoscoliosis (Cobb angle, 140°) in neurofibromatosis was operated for correction and posterior spinal fusion surgery, using pedicle screw instrumentation. Intraoperative neuromonitoring did not show any change in MEPs throughout the procedure, however, she woke-up with paraplegia. Immediate implant release could not recover her neurology functionally at last follow-up. Positive event during the operation was massive blood loss which could not show drop in MEPs as an ischemic cord injury (probable cause). Postoperative CT scan in both patients did not show any injury with pedicle screw as implants were well placed within the pedicles. Reviewing the literature, we could not find out any prospective study in animals identifying false-negative results with MEPs. Conclusion. From our experience of false-negative MEPs, we conclude that unwanted events with use of MEP in scoliosis or other spinal surgeries. We propose further prospective research on animals to solve this issue. We report a case of false-negative motor-evoked potentials (MEP) during the scoliosis surgery. A 15-year old girl with severe kyphoscoliosis was operated for correction with transcranial-MEP monitoring. Transcranial-MEP were maintained throughout surgery, however, she woke-up with paraplegia. Immediate release of construct could not recover neurology at final follow-up.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.921
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.335
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it