Bibliographic record
Abstract
The status of suppressor cells in patients with allergic rhinitis or asthma was studied. This latter group showed absent concanavalin A (ConA)-inducible suppressor cell function as measured by proliferative responses to pokeweed mitogen (PWM) and decreased function as measured by responses to phytohemagglutinin (PHA) or ConA. Patients with rhinitis showed values intermediate between normals and asthmatics. Similarly, preincubation in medium enhanced proliferative responses in normal and rhinitis patients but not in asthmatics, suggesting an absence of a short-lived suppressor cell population in the latter group. Suppressor cell function correlated negatively with log10 of serum IgE concentrations. Theophylline-sensitive suppressor cell numbers were slightly decreased in rhinitis patients and significantly so in asthmatics (p less than 0.01). In vitro preincubation of normal lymphocytes with aminophylline or isoproterenol (10 micrograms/ml) enhanced subsequent proliferative responses to PWM. Little enhancement was observed with cells from rhinitis patients, and actual depression was seen with cells from asthmatics, suggesting abnormal immunomodulatory effects of cyclic-AMP active drugs in this group of patients.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".