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Record W2089454467 · doi:10.1053/j.gastro.2014.06.005

Variants in Nicotinamide Adenine Dinucleotide Phosphate Oxidase Complex Components Determine Susceptibility to Very Early Onset Inflammatory Bowel Disease

2014· article· en· W2089454467 on OpenAlexafffund
Ramzi Fattouh, Abdul Elkadri, Wei Xu, Ryan Murchie, Thomas D. Walters, Conghui Guo, David R. Mack, Hien Q. Huynh, Shairaz Baksh, Mark S. Silverberg, Anne M. Griffiths, Scott B. Snapper, John H. Brumell, Aleixo M. Muise

Bibliographic record

VenueGastroenterology · 2014
Typearticle
Languageen
FieldImmunology and Microbiology
TopicNeutrophil, Myeloperoxidase and Oxidative Mechanisms
Canadian institutionsMount Sinai HospitalChildren's Hospital of Eastern OntarioStollery Children's HospitalHospital for Sick ChildrenPrincess Margaret Cancer CentreUniversity of TorontoSickKids Foundation
FundersNational Institute of Allergy and Infectious DiseasesNational Institute of Diabetes and Digestive and Kidney DiseasesNational Heart, Lung, and Blood InstituteCanada Foundation for InnovationHospital for Sick ChildrenOntario Innovation TrustNational Institutes of HealthCanadian Institutes of Health ResearchLeona M. and Harry B. Helmsley Charitable Trust
KeywordsNicotinamide adenine dinucleotide phosphateInflammatory bowel diseaseNicotinamide adenine dinucleotideOxidase testChemistryPhosphateBiochemistryFlavin adenine dinucleotideNicotinamideDiseaseMedicineEnzymeInternal medicineNAD+ kinaseCofactor

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.471
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.226
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations119
Published2014
Admission routes2
Has abstractno

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