Perioperative Myocardial Infarction in Patients Undergoing Noncardiac Surgery
Bibliographic record
Abstract
Letters4 October 2011Perioperative Myocardial Infarction in Patients Undergoing Noncardiac SurgeryP.J. Devereaux, MD, PhD, Gordon Guyatt, MD, MSc, and Salim Yusuf, MBBS, DPhilP.J. Devereaux, MD, PhDFrom Hamilton General Hospital, Hamilton, Ontario L8L 2X2, Canada; McMaster University, Hamilton, Ontario L8N 3Z5, Canada; and Hamilton General Hospital, Hamilton, Ontario L8L 2X2, Canada.Search for more papers by this author, Gordon Guyatt, MD, MScFrom Hamilton General Hospital, Hamilton, Ontario L8L 2X2, Canada; McMaster University, Hamilton, Ontario L8N 3Z5, Canada; and Hamilton General Hospital, Hamilton, Ontario L8L 2X2, Canada.Search for more papers by this author, and Salim Yusuf, MBBS, DPhilFrom Hamilton General Hospital, Hamilton, Ontario L8L 2X2, Canada; McMaster University, Hamilton, Ontario L8N 3Z5, Canada; and Hamilton General Hospital, Hamilton, Ontario L8L 2X2, Canada.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-155-7-201110040-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Potyk states that we did not comment on the effects of perioperative β-blockade. On the basis of all the β-blocker trials in patients undergoing noncardiac surgery, there is strong evidence that β-blockade prevents perioperative MI. Contrary to Dr. Potyk's statement, perioperative β-blockade probably increases the risk for death and almost certainly increases the risk for stroke (1, 2). Our interpretation of these data is that controlling the sympathetic system in the perioperative setting is beneficial, but we need to find a way to do it safely and practically.Dr. Potyk believes that it is not necessary to ...References1. Devereaux PJ, Yang H, Yusuf S, Guyatt G, Leslie K, Villar JC, et al; POISE Study Group. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet. 2008;371:1839-47. [PMID: 18479744] CrossrefMedlineGoogle Scholar2. Bangalore S, Wetterslev J, Pranesh S, Sawhney S, Gluud C, Messerli FH. Perioperative beta blockers in patients having non-cardiac surgery: a meta-analysis. Lancet. 2008;372:1962-76. [PMID: 19012955] CrossrefMedlineGoogle Scholar3. Levy M, Heels-Ansdell D, Hiralal R, Bhandari M, Guyatt G, Yusuf S, et al. Prognostic value of troponin and creatine kinase muscle and brain isoenzyme measurement after noncardiac surgery: a systematic review and meta-analysis. Anesthesiology. 2011;114:796-806. [PMID: 21336095] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: P.J. Devereaux, MD, PhD; Gordon Guyatt, MD, MSc; Salim Yusuf, MBBS, DPhilAffiliations: From Hamilton General Hospital, Hamilton, Ontario L8L 2X2, Canada; McMaster University, Hamilton, Ontario L8N 3Z5, Canada; and Hamilton General Hospital, Hamilton, Ontario L8L 2X2, Canada.Note: Drs, Devereaux, Guyatt, and Yusuf are responding on behalf of the POISE investigators.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-2129. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCharacteristics and Short-Term Prognosis of Perioperative Myocardial Infarction in Patients Undergoing Noncardiac Surgery P.J. Devereaux , Denis Xavier , Janice Pogue , Gordon Guyatt , Alben Sigamani , Ignacio Garutti , Kate Leslie , Purnima Rao-Melacini , Sue Chrolavicius , Homer Yang , Colin MacDonald , Alvaro Avezum , Luc Lanthier , Weijiang Hu , and Salim Yusuf , on behalf of the POISE (PeriOperative ISchemic Evaluation) InvestigatorsPerioperative Myocardial Infarction in Patients Undergoing Noncardiac Surgery Darryl Potyk Metrics 4 October 2011Volume 155, Issue 7Page: 477-478KeywordsAdjusted odds ratioDeath ratesDecision makingDisclosureMortalityMyocardial infarctionStatinsStrokeSurgeryTroponin ePublished: 4 October 2011 Issue Published: 4 October 2011 Copyright & PermissionsCopyright © 2011 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.010 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.011 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".