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Record W2091434654 · doi:10.2310/7070.2002.21285

Anti-inflammatory Effects of the Macrolides

2002· review· en· W2091434654 on OpenAlexaffvenue
Ross Davidson, Louis Péloquin

Bibliographic record

VenueThe Journal of Otolaryngology · 2002
Typereview
Languageen
FieldMedicine
TopicRespiratory and Cough-Related Research
Canadian institutionsQueen Elizabeth II Health Sciences Centre
Fundersnot available
KeywordsMedicineClinical trialRespiratory tractRespiratory tract infectionsAntibacterial agentIntensive care medicineAntibioticsImmunologyRespiratory systemInternal medicineMicrobiology

Abstract

fetched live from OpenAlex

Since their introduction into clinical practice, the macrolides have played an important role in the treatment of both upper and lower respiratory tract disease. In addition to their antibacterial effects, increased evidence is mounting to suggest that the macrolides possess other clinically relevant properties, such as anti-inflammatory and immunomodulatory activities. Several in vitro and clinical trials have been published supporting this hypothesis. This article reviews some of the evidence.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.950
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.323
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2002
Admission routes2
Has abstractyes

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