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Record W2092694160 · doi:10.1136/bmj.323.7305.119

The third generation pill controversy (“continued”)

2001· letter· en· W2092694160 on OpenAlexaboutno aff
James Drife

Bibliographic record

VenueBMJ · 2001
Typeletter
Languageen
FieldMedicine
TopicReproductive Health and Contraception
Canadian institutionsnot available
Fundersnot available
KeywordsDesogestrelPillMedicineGestodeneQuarter (Canadian coin)PublicityLevonorgestrelThird generationFirst generationFamily planningObstetricsDeveloped countryGynecologyFamily medicinePopulationResearch methodologyEnvironmental healthLawPolitical scienceHistoryPharmacology

Abstract

fetched live from OpenAlex

Papers p 131 The debate about the safety of third generation oral contraceptives shows no sign of fading away. Since it began in 1995 the main participants have been epidemiologists and clinical pharmacologists. There has been little input from the clinicians who prescribe oral contraceptives or from the women who use them. About 80% of British women use the pill at some time between the ages of 16 and 24.1 It was this age group that paid the price of the October 1995 scare, prompted by the publicity surrounding the announcement of the Committee on Safety of Medicines that third generation oral contraceptives had a higher risk of inducing venous thromboembolism. In the first quarter of 1996 in England and Wales there were 6198 more abortions than in the previous quarter (a 16% rise), and the increase continued more slowly until 1998.2 Doctors who counsel women with unplanned pregnancy are still angry about the amount of human misery caused by information mismanagement. The 1995 scare arose from three studies that reported that the risk of venous thromboembolism among users of pills containing levonorgestrel was half that of pills containing desogestrel or gestodene—the so called “third generation” progestogens. Over the following five years, …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.189
Threshold uncertainty score0.534

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.324
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations21
Published2001
Admission routes1
Has abstractyes

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