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Record W2093212492 · doi:10.1007/s11724-007-0062-3

Dopamine et douleur : une revue de littérature

2007· article· fr· W2093212492 on OpenAlexaff
Stéphane Potvin, Sylvain Grignon

Bibliographic record

VenueDouleur et Analgésie · 2007
Typearticle
Languagefr
FieldNeuroscience
TopicPain Management and Placebo Effect
Canadian institutionsUniversité de Sherbrooke
Fundersnot available
KeywordsMedicinePhilosophyPsychology

Abstract

fetched live from OpenAlex

Dans le présent article, nous passons en revue la littérature émergente suggérant un rôle clé de la dopamine dans la perception de la douleur, incluant : (i) des études en tomographie par émission de positrons ciblant les récepteurs dopaminergiques D2 ; (ii) des études génétiques sur les récepteurs de la dopamine et l’une de ses enzymes de dégradation ; (iii) des études pharmacologiques mesurant les effets sur la douleur des antiparkinsoniens, du bupropion et des antipsychotiques ; de même que (iv) des études induisant des douleurs expérimentales auprès de pathologies neuropsychiatriques (maladie de Parkinson et schizophrénie) où la dopamine est dysfonctionnelle. Nous proposons ensuite comme hypothèse intégrative que la dopamine serait impliquée dans les systèmes de modulation de la douleur, et suggérons d’investiguer le rôle de ce neurotransmetteur dans les conditions douloureuses où ces systèmes fonctionnent anormalement, comme c’est le cas dans la fibromyalgie.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.015
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.736
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0150.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.003
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.297
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2007
Admission routes1
Has abstractyes

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