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Record W2094502587 · doi:10.1118/1.3476217

Sci-Sat AM(2): Brachy - 05: Fast Monte Carlo Dose Calculations for Brachytherapy with BrachyDose

2010· article· en· W2094502587 on OpenAlexaff
RM Thomson, G. Yeğin, REP Taylor, JGH Sutherland, DWO Rogers

Bibliographic record

VenueMedical Physics · 2010
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsCarleton University
Fundersnot available
KeywordsKermaBrachytherapyMonte Carlo methodImaging phantomVoxelComputer scienceDosimetryRadiation treatment planningDICOMComputational sciencePhysicsNuclear medicineMedical physicsRadiation therapyOpticsMathematicsArtificial intelligenceMedicineStatistics

Abstract

fetched live from OpenAlex

A fast dose calculation algorithm called BrachyDose has been developed for brachytherapy applications. BrachyDose is based on the EGSnrc code system for simulating radiation transport. Complex geometries are modelled through the superposition of basic geometric entities (spheres, cuboids, cylinders, and cones) using Yegin's multi-geometry package; the phantom geometry may be defined using a CT dataset. A database of brachytherapy sources has been developed and benchmarked, as has a database of eye plaque applicators. BrachyDose scores collision kerma, which is equivalent to absorbed dose for most situations of interest, using a tracklength estimator. The phase space of particles emitted from brachytherapy sources may be generated with BrachyDose and used in subsequent simulations to avoid the repeated simulation of particle transport within sources. A particle recycling feature has been implemented for multisource configurations in which the first source acts as a particle generator; particles emitted from this source are reinitiated at each source location. Dose calculations for prostate permanent implants achieving 2% average uncertainty in the prostate region take less than 30 seconds in (2 mm)3 voxels on a single 3.0 GHz Woodcrest core; calculation times for eye plaque therapy are on the order of three minutes in (0.5 mm)3 voxels. These calculation times are sufficiently fast for routine clinical treatment planning. A graphical user interface (GUI) for BrachyDose has been developed. Working towards clinical implementation, efforts are underway to integrate data in the DICOM-RT format with BrachyDose.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.226
Threshold uncertainty score0.756

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0030.002
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.2260.083

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.289
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations26
Published2010
Admission routes1
Has abstractyes

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