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Record W2094577127 · doi:10.1159/000082130

Adult Neural Stem Cells: Attempting to Solve the Identity Crisis

2004· review· en· W2094577127 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueDevelopmental Neuroscience · 2004
Typereview
Languageen
FieldNeuroscience
TopicNeurogenesis and neuroplasticity mechanisms
Canadian institutionsToronto Rehabilitation InstituteUniversity of Toronto
Fundersnot available
KeywordsNeural stem cellEmbryonic stem cellNeuroscienceStem cellBiologyNeuroepithelial cellNeurosphereCentral nervous systemIn vivoAdult stem cellPopulationCell biologyMedicineGenetics

Abstract

fetched live from OpenAlex

A prevailing view in the literature is that the central nervous system (CNS) develops from a population of self-renewing, multipotential stem cells that persist throughout life. The in vivo identification and isolation of this rare subpopulation of cells has been the focus of much attention. This review will discuss the in vivo characterization of neural stem cells in the embryonic and adult CNS and some recent discrepancies and limitations between in vivo and in vitro assays used to identify neural stem cells.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.625
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.003
Science and technology studies0.0020.000
Scholarly communication0.0010.001
Open science0.0040.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.113
GPT teacher head0.327
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it