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Record W2094652164 · doi:10.1109/iscas.2014.6865104

Biosensor systems and applications in genomics, proteomics and metabolomics: A review

2014· review· en· W2094652164 on OpenAlexaff
Scott MacKay, Jie Chen

Bibliographic record

Venuenot available
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced biosensing and bioanalysis techniques
Canadian institutionsNational Institute for NanotechnologyUniversity of Alberta
Fundersnot available
KeywordsBiosensorGenomicsBiomoleculeComputer scienceProteomicsMetabolomicsAptamerNanotechnologyComputational biologyBioinformaticsBiologyGenomeMaterials science

Abstract

fetched live from OpenAlex

This article provides a brief overview and background on current biosensor designs for applications in genomics, proteomics and metabolomics. As research continues in many different aspects of biosensor design, new and better ways to recognize and detect low concentrations of a wide variety of different biomolecules are being developed for various applications. Biosensors can offer a simpler, faster and cheaper alternative to the testing that is often required to collect the large amounts of data for genomic, proteomic and metabolomic sensing. Recognition elements such as DNA aptamers make detecting very different types of biomolecules in the same system possible, while the use of signal-enhancing nanoparticle probes and microfabricated sensor arrays make it possible to test for a large number of different target biomolecules quickly and effectively.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.004
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0040.004
Science and technology studies0.0010.001
Scholarly communication0.0010.003
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.317
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2014
Admission routes1
Has abstractyes

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