Physiological Activity of Neuropeptide F on the Hindgut of the Blood-Feeding Hemipteran,<i>Rhodnius prolixus</i>
Bibliographic record
Abstract
Current hypotheses propose that, in the invertebrates, neuropeptide F (NPF), the vertebrate NPY homologue, may be capable of regulating responses to diverse cues related to nutritional status and feeding. An investigation into the effects of Drosophila melanogaster NPF (DrmNPF) and Anopheles gambiae NPF (AngNPF) on hindgut physiology of Rhodnius prolixus Stal (Heimptera: Reduviidae) suggests a myoinhibitory role for these peptides and the R. prolixus native peptide. Extracts of the central nervous system of R. prolixus were processed and several HPLC-fractions revealed NPF-like activity within the nanomolar equivalent range when tested using the hindgut contraction assay. Although NPF has been shown to decrease epithelial membrane potential in Aedes aegypti larval midgut preparations, NPF does not appear to play a role in epithelial transport of potassium in the hindgut. While the function of NPF has yet to be established, NPF-like effects suggest multiple physiological roles for NPF among invertebrates.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".