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Record W2095412167 · doi:10.1159/000131575

A search for a genetic basis for gonosomal univalency in mice

2008· article· en· W2095412167 on OpenAlex
B. Bhaskar Gollapudi, O.P. Kamra, Stan R. Blecher

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCytogenetics and Cell Genetics · 2008
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Canadian institutionsDalhousie University
Fundersnot available
KeywordsInbred strainBiologyGeneticsMolecular biologyMetaphaseChromosomeGene

Abstract

fetched live from OpenAlex

The frequencies of cells with XY nonpairing at diakinesis/metaphase I were examined in random-bred ICR-Swiss, partly inbred DCH, and highly inbred DBA/2J and C57BL/6-bgJ mice. The animals in given inbred line displayed homogeneity in the proportion of cells with gonosomal univalents. In DBA/2J, the X and Y remained unpaired in 33.2% of the cells examined, whereas the corresponding frequency in C57BL/6-bgJ was only 7.0%. Previous data of RAPP et al. (1977) showed a low incidence of XY nonassociation in C57BL/6 and high frequencies in the BDF1 hybrid (C57BL6 female X DBA/2 male). We interpret our results, and the previous data of RAPP et al. (1977), to indicate the existence in mice of a genetic polymorphism for XY nonassociation. The DBA/2J strain appears to have factors that predispose to a high frequency of gonosomal univalency.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.104
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.269
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it