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Record W2095981999 · doi:10.1002/047084289x.rp065

(Phenyldimethylsilyl)methoxymethyl Chloride

2001· reference-entry· en· W2095981999 on OpenAlexaff
J. Michael Chong

Bibliographic record

VenueEncyclopedia of Reagents for Organic Synthesis · 2001
Typereference-entry
Languageen
FieldChemistry
TopicInorganic and Organometallic Chemistry
Canadian institutionsUniversity of Waterloo
Fundersnot available
KeywordsChemistryReagentFormaldehydeChlorideSolubilityALUMINUM HYDRIDEEthyl ChlorideHydrogen chlorideHydrolysisLithium chlorideLithium (medication)Organic chemistryHydrideInorganic chemistryNuclear chemistryHydrogenIon

Abstract

fetched live from OpenAlex

[128784-94-1] C10H15ClOSi (MW 214.79) InChI = 1S/C10H15ClOSi/c1-13(2,9-12-8-11)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3 InChIKey = GYTNOYKTOZHTPQ-UHFFFAOYSA-N (reagent for the protection of hydroxyl groups1) Alternate Name: SMOM-Cl. Solubility: sol most organic solvents. Preparative Method: prepared by a three-step sequence starting from (chloromethyl)dimethylphenylsilane. Displacement with NaOAc followed by reduction with Lithium Aluminum Hydride furnishes PhMe2SiCH2OH. Subsequent reaction with Formaldehyde–Hydrogen Chloride provides the crude chloride (>90% pure) which can be used without further purification. Handling, Storage, and Precautions: although stability and toxicological data for this compound are not available, it is expected to be readily hydrolyzed, toxic, and carcinogenic.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.131
Threshold uncertainty score0.437

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.002
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0040.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.1310.140

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.247
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2001
Admission routes1
Has abstractyes

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Same venueEncyclopedia of Reagents for Organic SynthesisSame topicInorganic and Organometallic ChemistryFrench-language works237,207