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Record W2096182787 · doi:10.4172/1488-5069.1000011

Andropause and depression: A perspective for the clinician

2001· article· en· W2096182787 on OpenAlexvenueno aff
Brian Bexton

Bibliographic record

VenueJournal of Sexual & Reproductive Medicine · 2001
Typearticle
Languageen
FieldMedicine
TopicHormonal and reproductive studies
Canadian institutionsnot available
Fundersnot available
KeywordsPerspective (graphical)Depression (economics)PsychologyPsychotherapistComputer scienceArtificial intelligenceEconomics

Abstract

fetched live from OpenAlex

M enopause in women is a distinct clinical entity with clear signs and symptoms.It is a normal and natural event that usually occurs in women in their fourth and fifth decades of life.Ovarian function ceases, resulting in a significant diminution in estrogen production, anovulation and the cessation of menses.During the perimenopausal period, women may have physical symptoms, such as hot flushes and decreased vaginal secretions, and they may also experience dysphoria.The incidence of major depression is also increased during the perimenopausal period.Estrogen supplements may decrease dysphoria and can potentiate the effect of antidepressants in major depression.Andropause is less well-recognized as a clear syndrome in aging men.Unlike menopause in women, men may remain fertile even during their seventh and eighth decades of life.Also, unlike the rapid decreases in hormonal levels in women that occur during menopause, total testosterone levels in men remain more stable over the years.However, finer analysis shows that the active fraction of testosterone (bioavailable testosterone) decreases progressively after age 40 years.Thus, andropause does not have the same connotation as menopause because hormonal secretions continue.The World Health Organization recognizes the existence of a clinical syndrome characterized by a partial androgen deficiency in aging males.Thus, the physical and emotional effects of declining hormone secretion in men are less dramatic and less obvious than those experienced by women.However, in aging men, the syndrome of andropause develops progressively, and may consist of physical, sexual

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.014
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.033
Threshold uncertainty score0.040

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.014
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0020.001
Science and technology studies0.0050.004
Scholarly communication0.0050.015
Open science0.0030.004
Research integrity0.0330.028
Insufficient payload (model declined to judge)0.0120.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.066
GPT teacher head0.383
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2001
Admission routes1
Has abstractyes

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