Effect of self-assembled monolayers (SAMs) in binding glucose oxidase for electro-enzymatic glucose sensor with gold electrodes
Bibliographic record
Abstract
In this paper, a new approach to improve long term stability of electro-enzymatic glucose sensors is presented. Self-assembled monolayers (SAMs) are employed for surface treatment of the gold electrodes to improve adhesion. Three types of functional alkylthiols, namely 11-amino-1-undecanethiol hydrochloride, 1-hexadecanethiol (1-hydrochloride, and 1,9-nonanedithiol, and bovine serum albumin (BSA) are investigated in our study. Alkylhiols are used for surface treatment of gold electrodes and BSA is mixed in enzyme (glucose oxidase) solution to realize the proposed sensors. Furthermore, gold is investigated as an electrode material. Both reference and active electrodes are fabricated using only gold. The current response of the modified sensors showed long term stability. However, the unmodified sensors showed very short term stability because glucose oxidase does not adhere well to the electrodes. The proposed modified sensors also show lower drift than the unmodified sensors without surface treatment and BSA.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".