The effect of the implementation of therapeutic hypothermia on fluid balance and incidence of hyponatremia in neonates with moderate or severe hypoxic-ischaemic encephalopathy
Bibliographic record
Abstract
AIM: To investigate the effect of the therapeutic hypothermia (TH), used in infants with moderate or severe hypoxic-ischaemic encephalopathy (HIE), on fluid balance and incidence of hyponatremia. METHODS: Retrospective cohort study of moderate and severe HIE infants before (pre) and after (post) TH implementation. Daily fluid and electrolytes intake/output were collected from the medical records of each patient from day 1 to day 4 of life. Hyponatremia was defined as sodium <130 mEq/L. RESULTS: A total of 67 infants were studied: pre-TH = 29 and post-TH = 38. Infants in the post-TH group had greater weight gain [140 g (62, 227) vs. 10 g (-100, 105) p < 0.001] and lower serum sodium (130.9 ± 4.5 mmol/L vs. 133.4 ± 5.7, p = 0.008). The incidence of hyponatremia increased from 48 to 76% (p = 0.02). CONCLUSION: In our centre, the implementation of TH was followed by an increased fluid retention and higher incidence of hyponatremia. Centres adopting TH should have clear guidelines for fluid and electrolyte management.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".