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Record W2097609335 · doi:10.1002/ange.200702965

Hugo (Ugo) Schiff, Schiff‐Basen und hundert Jahre β‐Lactam‐Synthese

2007· article· de· W2097609335 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAngewandte Chemie · 2007
Typearticle
Languagede
FieldChemistry
TopicSynthesis of β-Lactam Compounds
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsSchiff baseChemistryImineMedicinal chemistryStereochemistryOrganic chemistryCatalysis

Abstract

fetched live from OpenAlex

Der Mann hinter der Base: Hugo Schiff (1834–1915) war ein Schüler Friedrich Wöhlers in Deutschland, verbrachte jedoch seiner freidenkerischen Ansichten wegen fast seine gesamte akademische Laufbahn in Italien, wo er, neben zahlreichen anderen Errungenschaften, die Schiff-Basen (Imine) entdeckte und charakterisierte. Sein wissenschaftliches Wirken erstreckte sich über einen Zeitraum von über 60 Jahren, und es war ihm vergönnt, die Anwendung der Schiff-Basen in [2+2]-Cycloadditionen mit Ketenen zur Bildung von β-Lactamen zu erleben.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.323
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0060.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.277
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it