MétaCan
Menu
Back to cohort
Record W2098380717 · doi:10.1016/j.ab.2008.11.021

A global benchmark study using affinity-based biosensors

2008· article· en· W2098380717 on OpenAlexaff
Rebecca L. Rich, Giuseppe A. Papalia, Peter J. Flynn, Jamie Furneisen, John G. Quinn, Joshua S. Klein, Phinikoula S. Katsamba, M. Brent Waddell, Michael J. Scott, Joshua Thompson, Judie Berlier, Schuyler Corry, Mireille Baltzinger, Gabrielle Zeder‐Lutz, Andreas Schoenemann, Anca Clabbers, Sébastien Wieckowski, Mary M. Murphy, Phillip C. Bulman Page, Thomas E. Ryan, Jay Duffner, Tanmoy Ganguly, John Corbin, Satyen Gautam, Gregor Anderluh, Andrej Bavdek, Dana Reichmann, Satya Prakash Yadav, Eric Hommema, Ewa Pol, Andrew W. Drake, Scott L. Klakamp, Trevor Chapman, Dawn Kernaghan, Ken Miller, Jason T. Schuman, Kevin C. Lindquist, Kara Herlihy, Michael Murphy, Richard N. Bohnsack, Bruce Andrien, Pietro Brandani, Danny Terwey, Rohn Millican, Ryan J. Darling, Liann Wang, Quincy Carter, Joe E. Dotzlaf, Jacinto López‐Sagaseta, Islay Campbell, Paola Torreri, Sylviane Hoos, Patrick England, Yang Liu, Yasmina Abdiche, Daniel Malashock, Alanna Pinkerton, Melanie Wong, Eileen M. Lafer, Cynthia S. Hinck, Kevin Thompson, Carmelo Di Primo, Alison Joyce, Jonathan Brooks, Federico Torta, Anne Birgitte Bagge Hagel, Janus Krarup, Jesper Pass, Mônica Siqueira Ferreira, Sergei Shikov, Malgorzata G. Mikolajczyk, Yuki Abe, Gaetano Barbato, Anthony M. Giannetti, Ganeshram Krishnamoorthy, Bianca Beusink, Daulet K. Satpaev, Tiffany Tsang, Eric Fang, J. E. Partridge, Stephen G. Brohawn, James R. Horn, Otto Pritsch, Gonzalo Obal, S. Nilapwar, Ben Busby, Gerardo Gutiérrez‐Sánchez, Ruchira Das Gupta, Sylvie Canépa, Krista Witte, Zaneta Nikolovska‐Coleska, Yun Hee Cho, Roberta D’Agata, Kristian H. Schlick, R. Calvert, Eva Muñoz, María J. Hernáiz, Tsafir Bravman, Monica Dines, Min-Hsiang Yang, Ágnes Puskás, Jiejin Li, Martin A. Wear, Asya V. Grinberg, Jason Baardsnes, Olan Dolezal, Melicia R. Gainey, Henrik Anderson, Jinlin Peng, Mark A. Lewis, Peter Spies, Quyhn Trinh, Sergei I. Bibikov, J. Raymond, Mohammed Yousef, Vidya Chandrasekaran, Yuguo Feng, Anne W. Emerick, Suparna Mundodo, Rejane Guimaraes, Katy McGirr, Yue-Ji Li, Heather Hughes, Hubert Mantz, Rostislav Škrabana, Mark R. Witmer, Joshua B. Ballard, Loic Martin, Petr Skládal, George Korza, Ite A. Laird‐Offringa, Charlene S. Lee, Abdelkrim Khadir, Frank Podlaski, Phillippe Neuner, Julie Rothacker, Ashique Rafique, Nico Dankbar, Peter Kainz, Erk Gedig, Momchilo Vuyisich, Christina Boozer, Nguyễn Hoàng Ly, Mark Toews, Aykut Üren, Oleksandr Kalyuzhniy, Kenneth B. Lewis, Eugene Chomey, Brian J. Pak, David G. Myszka

Bibliographic record

VenueAnalytical Biochemistry · 2008
Typearticle
Languageen
FieldMedicine
TopicMonoclonal and Polyclonal Antibodies Research
Canadian institutionsBio-Rad (Canada)National Research Council CanadaBiotechnology Research Institute
FundersNational Center for Research ResourcesNational Cancer Institute
KeywordsBiosensorAnalyteChemistryChromatographyDissociation constantOutlierAnalytical Chemistry (journal)BiochemistryMathematicsStatistics

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.011
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.004
Science and technology studies0.0010.001
Scholarly communication0.0030.003
Open science0.0030.002
Research integrity0.0030.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.365
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations97
Published2008
Admission routes1
Has abstractno

Explore more

Same venueAnalytical BiochemistrySame topicMonoclonal and Polyclonal Antibodies ResearchFrench-language works237,207