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Record W2098458410 · doi:10.3109/713610282

Tooth Rings: Dental Enamel as a Chronological Biomonitor of Elemental Absorption from Pregnancy to Adolescence

2003· article· en· W2098458410 on OpenAlexaff
Alan H. Goodman, Alexis E. Dolphin, Dulasiri Amarasiriwardena, Rebecca Klein, Jeffrey R. Backstrand, John B. Reid, P.M. Outridge

Bibliographic record

VenueJournal of Children s Health · 2003
Typearticle
Languageen
FieldArts and Humanities
TopicForensic Anthropology and Bioarchaeology Studies
Canadian institutionsGeological Survey of Canada
FundersNational Science Foundation
KeywordsEnamel paintDeciduous teethPregnancyZincIn uteroDentistryTooth enamelChemistryFetusMedicineBiology

Abstract

fetched live from OpenAlex

Because the dental hard tissues commence development in the 13th week in utero and once formed are essentially inert, they may provide unique windows onto environmental and physiological changes during pregnancy and early life. We review the general potential of teeth as biomonitors and then the development of laser ablation-inductively coupled-plasma mass spectrometry (LA-ICP-MS) to assess elemental absorption over temporal periods from a few days to years. In studies of exfoliated deciduous incisors of infants from Solis, Mexico (n=38), we found dramatic increases in lead and zinc from prenatal to postnatal enamel as well as strong correlations (∼ 0.5 to 0.9) between prenatal and postnatal enamel intensities of strontium barium, zinc, and lead. Prenatal enamel zinc is negatively correlated with dietary factors inhibiting absorption such as mothers' maize, phytate, and calcium intake during pregnancy. Prenatal enamel lead intensities, possibly from lead-glazed pottery, are inversely correlated with height (r=−0.53) and weight (r=−0.48) at ∼ 5 years. The combination of micro-spatial chemical methods such as LA-ICP-MS with the kymographic development of teeth illustrates the potential of enamel to monitor metal absorption and provide insights into the source, timing, and epidemiological consequences of early life pollution and nutrition.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.160
Threshold uncertainty score0.808

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.289
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2003
Admission routes1
Has abstractyes

Explore more

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