Production of PRRSV-negative pigs commingled from multiple, vaccinated, serologically stable, PRRSV-positive breeding herds
Bibliographic record
Abstract
Objectives: To determine whether PRRSV-negative pigs could be produced from multiple PRRSV-positive herds and to investigate the serological stability of these herds and the impact of sow vaccination. Methods: Piglets originating from non-vaccinated and vaccinated herds were weaned at 8 to 14 days and housed separately in an off-site nursery for 90 days. Pigs were tested by PRRS IDEXX ELISA at weaning and at 30, 60, and 90 days of age. A subset of pigs was tested using PRRS reverse transcription-polymerase chain reaction (RT-PCR) and restriction fragment length polymorphism (RFLP) assays. Serological stability of breeding herds was assessed by PRRS IDEXX ELISA. Results: The five vaccinated herds were serologically stable. Piglets from these herds became seronegative after weaning and remained PRRSV negative up to 90 days of age. Pigs from two of the five non-vaccinated herds were PRRSV negative. One of these herds was serologically stable. Piglets from the other three non-vaccinated herds were PRRSV positive at weaning, and the number of seropositive piglets and their S:P values increased to 90 days of age. Two of these herds were not serologically stable. After vaccination of open sows and gilts, PRRSV-negative pigs were produced from one of these two herds. Implications: Piglets weaned at 8 to 14 days from multiple, serologically stable sow herds and commingled were PRRSV negative at 90 days of age. Vaccinating gilts twice prior to breeding and sows at weaning may increase the stability of breeding herds. Results must be validated in large commercial operations.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".