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Record W2102239241 · doi:10.1155/s0161171203209224

Subthreshold domain of bistable equilibria for a model of HIVepidemiology

2003· article· en· W2102239241 on OpenAlexafffund
Brandon Corbett, Seyed M. Moghadas, Abba B. Gumel

Bibliographic record

VenueInternational Journal of Mathematics and Mathematical Sciences · 2003
Typearticle
Languageen
FieldMedicine
TopicMathematical and Theoretical Epidemiology and Ecology Models
Canadian institutionsUniversity of Manitoba
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsBistabilitySubthreshold conductionMathematicsMixing (physics)Human immunodeficiency virus (HIV)Stability (learning theory)PopulationDomain (mathematical analysis)Basic reproduction numberTransmission (telecommunications)HomogeneousStatistical physicsApplied mathematicsMathematical analysisVirologyEnvironmental healthMedicinePhysicsComputer scienceCombinatoricsQuantum mechanicsTelecommunications

Abstract

fetched live from OpenAlex

A homogeneous‐mixing population model for HIV transmission, which incorporates an anti‐HIV preventive vaccine, is studied qualitatively. The local and global stability analysis of the associated equilibria of the model reveals that the model can have multiple stable equilibria simultaneously. The epidemiological consequence of this (bistability) phenomenon is that the disease may still persist in the community even when the classical requirement of the basic reproductive number of infection ( ℛ 0 ) being less than unity is satisfied. It is shown that under specific conditions, the community‐wide eradication of HIV is feasible if ℛ 0 < ℛ ∗ , where ℛ ∗ is some threshold quantity less than unity. Furthermore, for the bistability case (which occurs when ℛ ∗ < ℛ 0 < 1), it is shown that HIV eradication is dependent on the initial sizes of the subpopulations of the model.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.206
Threshold uncertainty score0.589

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.080
GPT teacher head0.362
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2003
Admission routes2
Has abstractyes

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