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Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial

2015· article· en· 850 citations· W2103524303 on OpenAlex· 10.1016/s0140-6736(15)61134-5

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.033
GPT teacher head0.324
Teacher spread
0.291 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
The Lancet
Topic
Spondyloarthritis Studies and Treatments
Field
Medicine
Canadian institutions
Memorial University of Newfoundland
Funders
Medical Research CouncilNational Institute for Health and Care Research
Keywords
SecukinumabMedicinePsoriatic arthritisPlaceboInternal medicineClinical endpointRheumatologyArthritisPlacebo-controlled studyGastroenterologyClinical trialImmunologyDouble blindPathology
Has abstract in OpenAlex
no