A Mixed‐Culture Model of a Probiotic Biofilm Control System
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
We present a mathematical model and computer simulations for the control of a pathogenic biofilm by a probiotic biofilm. This is a substantial extension of a previous model of control of a pathogenic biofilm by microbial control agents that are suspended in the aqueous bulk phase (H. Khassehkhan and H.J. Eberl, Comp. Math. Meth. Med, 9(1) (2008), pp. 47-67). The mathematical model is a system of double-degenerate diffusion-reaction equations for the microbial biomass fractions probiotics, pathogens and inert bacteria, coupled with convection-diffusion-reaction equations for two growth controlling substrates, protonated lactic acids and hydrogen ions (pH). The latter are produced by the bacteria and become detrimental at high concentrations. In simulation studies, we find that the site of attachment of probiotics in the flow channel is crucial for success and efficacy of the probiotic control mechanism.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it