Angiotensin-converting enzyme inhibition and free-radical scavenging properties of cationic peptides derived from soybean protein hydrolysates
Bibliographic record
Abstract
Soybean protein isolate was hydrolyzed consecutively with pepsin and pancreatin followed by separation of the digest on a SP-Sepharose column to obtain angiotensin-converting enzyme (ACE)-inhibitory fractions. Three of the five fractions obtained inhibited ACE activity, with values of the concentration of hydrolysate fraction that inhibited 50% of ACE activity of 1.09, 0.42, and 0.25 mg/ml for fractions 2, 3, and 4, respectively. Kinetic analysis showed that fractions 2, 3, and 4 are non-competitive, competitive and mixed inhibitors of ACE, respectively. Fluorescence emission of ACE was quenched along with a red shift in wavelength of emission maxima in the presence of the protein hydrolysate fractions. Fraction 3 was the most potent free-radical scavenger, while fraction 4 had almost no scavenging effect. We concluded that fraction 3 had the most potential to be used as a bioactive ingredient because of its strong ACE-inhibitory and free-radical scavenging properties.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".